I read this book for my high school AP English class. We also read Beloved by Toni Morrison, and afterwards the teacher asked us to write a paper on which one we liked better and why. Which seems a little odd. But the point is that I was only one of two people in the class who preferred The Sound and the Fury, which I find kind of interesting.
It's a notoriously difficult book, but I remember that once I started reading a particular section and really got into the rhythm and feel of a character's thought processes, however confused and tortured they might be, I could actually kind of follow it. (I'm sure I missed some details here and there.) I'd never read anything like it, that was for sure.
I started to re-read it about five years ago but never finished for some reason. I should try it again.